Article
  • Preparation and In-Vitro Release Performance of Geranium Wilfordii Maxim Filled Biodegradable Microcapsules
  • Li M, Wang R, Liu X
  • Geranium Wilfordii Maxim이 봉입된 마이크로캡슐의 제조와 체외방출 성능
Abstract
Encapsulation of Geranium wilfordii Maxim (GWM) into polyvinyl alcohol (PVA) biodegradable microcapsules was performed using the interfacial polymerization method. The optimum synthesis conditions including the core/shell ratio and the emulsifier concentration were explored. The fabricated microcapsules were characterized by Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and thermogravimetric analysis (TGA). The in-vitro release behaviour of the GWM microcapsules was studied by ultraviolet-visible spectroscopy (UV-VIS). The results show that when the core/shell ratio was 1:1 and the emulsifier concentration was 5%, the GWM microcapsules sizes have a normal distribution with a mean diameter of 23.94 μm. FTIR results show that the GWM was successfully encapsulated by the PVA polymer. TG results indicate that the GWM microcapsules are stable below 300 °C. Moreover, the release from the GWM microcapsules occurs according to a non-Fickian diffusion model.

Keywords: traditional Chinese medicine extractive; microcapsule; slow-release; interfacial polymerization

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  • Polymer(Korea) 폴리머
  • Frequency : Bimonthly(odd)
    ISSN 0379-153X(Print)
    ISSN 2234-8077(Online)
    Abbr. Polym. Korea
  • 2023 Impact Factor : 0.4
  • Indexed in SCIE

This Article

  • 2017; 41(3): 404-412

    Published online May 25, 2017

  • 10.7317/pk.2017.41.3.404
  • Received on Sep 4, 2016
  • Accepted on Dec 30, 2016