Article
  • Synthesis and Thermo-responsive Properties of Amino Group Terminated Poly(N-isopropylacrylamide) and Sodium Alginate-g-Poly(N-isopropylacrylamide)
  • Lee EJ, Kim YH
  • 말단 아민기를 갖는 폴리(N-이소프로필아크릴아미드) 및 알긴산 나트륨-g-폴리(N-이소프로필아크릴아미드)의 합성과 열응답 특성
  • 이은주, 김영호
Abstract
Amino group-terminated poly(N-isopropylacrylamide) (PNIPAAm-NH2) was synthesized via a radical polymerization of N-isopropylacrylamide (NIPAAm) using 2-aminoethanethiol hydrochloride (AESH) as a chain transfer agent. The molecular weight of the PNIPAAm-NH2 was controlled by changing the concentration of AESH. The LCST of the aqueous solution of PNIPAAm-NH2 increased slightly with increasing the AESH concentration. Alginate-g- PNIPAAm copolymer was synthesized by grafting PNIPAAm-NH2 onto sodium alginate using N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide and N-hydroxysuccinimide. The formation of the grafted copolymers was confirmed by FTIR spectroscopy, solubility in water, and SEM-EDS. Alginate-g-PNIPAAm also exhibited swelling-deswelling behavior. However, it showed a LCST at a slightly increased temperature compared to PNIPAAm. The swelling ratio of the alginate-g-PNIPAAm hydrogel increased with the increase of the grafted PNIPAAm content.

열응답성 고분자인 폴리(N-이소프로필아크릴아미드) (PNIPAAm) 말단에 아민기를 갖는 PNIPAAm-NH2 및 이들 알긴산 나트륨에 그래프팅시킨 공중합체를 합성하고 이들의 여러 가지 특성들을 분석하였다. PNIPAAm-NH2를 합성하기 위하여 N-이소프로필아크릴아미드를 라디칼 중합할 때 2-aminoethanethiol hydrochloride (AESH)를 연쇄이동제로 사용하였다. AESH 농도를 높이면 PNIPAAm-NH2의 분자량이 작아지며 PNIPAAm-NH2 수용액의 하한 임계용액온도(LCST)가 낮아졌다. N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide 및 N-hydroxysuccinimide를 사용하여 PNIPAAm-NH2를 graft-onto 방법으로 알긴산 나트륨에 그래프팅시킨 alginate-g-PNIPAAm 공중합체 역시 온도에 따라 팽윤-수축 거동을 하였으며, PNIPAAm-NH2보다 약간 높은 온도에서 LCST를 나타내었고, 그래프트된 PNIPAAm의 양이 많아질수록 팽윤비가 커졌다.

Keywords: poly(N-isopropylacrylamide); sodium alginate; graft; thermo-responsive property; swelling.

References
  • 1. Liu F, Urban MW, Prog. Polym. Sci., 35, 33 (2010)
  •  
  • 2. Ahn JH, Jeon YS, Chung DJ, Kim JH, Polym.(Korea), 35(1), 94 (2011)
  •  
  • 3. Lim YH, Kim D, Lee DS, J. Appl. Polym. Sci., 64, 2647 (1990)
  •  
  • 4. Bajpai AK, Shukla SK, Bhanu S, Kankane S, Prog.Polym. Sci., 33, 1088 (2009)
  •  
  • 5. Kucking D, Richter A, Arndt KF, Macromol. Mat. Eng., 144, 288 (2003)
  •  
  • 6. Liang L, Feng XD, Martin PFC, Peurrung LM, J. Appl. Polym. Sci., 75(14), 1735 (2000)
  •  
  • 7. Hu JM, Liu SY, Macromolecules, 43(20), 8315 (2010)
  •  
  • 8. Kayaman N, Kazan D, Erarslan A, Okay O, Baysal BM, J. Appl. Polym. Sci., 67(5), 805 (1998)
  •  
  • 9. Weinhart M, Becherer T, Haag R, Chem. Commun., 47, 1553 (2011)
  •  
  • 10. Schmaljohann D, Adv. Drug Deliver. Rev., 58, 1655 (2006)
  •  
  • 11. Moon JR, Kim JH, Macromol. Res., 16(6), 489 (2008)
  •  
  • 12. Oh YJ, Lee G, Park SY, Polym.(Korea), 36(2), 223 (2012)
  •  
  • 13. Liu Y, Liu XY, Liu HJ, Cheng F, Chen Y, Macromol. Res., 20(6), 578 (2012)
  •  
  • 14. Schild HG, Prog. Polym. Sci., 17, 163 (1992)
  •  
  • 15. Fujii K, Ueki T, Niitsuma K, Matsunaga T, Watanabe M, Shibayama M, Polymer, 52(7), 1589 (2011)
  •  
  • 16. Boutris C, Chatzi EG, Kiparissides C, Polymer, 38(10), 2567 (1997)
  •  
  • 17. Deshmukh MV, Vaidya AA, Kulkarni MG, Rajamohanan PR, Ganapathy S, Polymer, 41(22), 7951 (2000)
  •  
  • 18. Wen OH, Kuroda S, Kubota H, Eur. Polym. J., 37, 807 (2001)
  •  
  • 19. Tauer K, Gau D, Schulze S, Volkel A, Dimova R, Colloid Polym. Sci., 287, 299 (2009)
  •  
  • 20. Yu R, Zheng S, J. Biomater. Sci., 22, 2305 (2011)
  •  
  • 21. Zhang RS, Polymer, 46(8), 2443 (2005)
  •  
  • 22. Cooperstein MA, Canavan HE, Langmuir, 26(11), 7695 (2010)
  •  
  • 23. Pourjavadi A, Amini-Fazl MS, Hosseinzadeh H, Macromol. Res., 13(1), 45 (2005)
  •  
  • 24. Han SM, Nam CW, Ko SW, J. Korean Fiber Soc., 37, 365 (2000)
  •  
  • 25. Teng S, Shi J, Peng B, Chen L, Compos. Sci. Technol., 66, 1532 (2006)
  •  
  • 26. Simpson NE, Stabler CL, Simpson CP, Sambanis A, Constantinidis I, Biomaterials., 25, 2603 (2004)
  •  
  • 27. Papageorgiou SK, Kouvelos EP, Favvas EP, Sapalidis AA, Romanos GE, Katsaros FK, Carbohyd. Res., 345, 469 (2010)
  •  
  • 28. Park SJ, Kang JY, Polym.(Korea), 29(4), 369 (2005)
  •  
  • 29. Socrates G, Infrared and Raman Characteristic Group Frequencies, John Wiley & Sons, New York (2001)
  •  
  • 30. Kutchko BG, Kim AG, Fuel, 85(17-18), 2537 (2006)
  •  
  • Polymer(Korea) 폴리머
  • Frequency : Bimonthly(odd)
    ISSN 0379-153X(Print)
    ISSN 2234-8077(Online)
    Abbr. Polym. Korea
  • 2023 Impact Factor : 0.4
  • Indexed in SCIE

This Article

  • 2013; 37(4): 539-546

    Published online Jul 25, 2013

  • Received on Mar 29, 2013
  • Accepted on Apr 28, 2013