Article
  • Syntheses and Swelling Behaviors of Poly(N-isopropylacrylamide-co-acrylonitrile) Hydrogels
  • Piao ZF, Ham MJ, Kim YH
  • Poly(N-isopropylacrylamide-co-acrylonitrile) 수화젤의 합성과 팽윤거동
  • Piao ZF, 함명조, 김영호
Abstract
Poly(N-isopropylacrylamide-co-acrylonitrile)[P(NIPAAm-co-AN)] copolymers with AN content of up to 10 mol% and their hydrogels were synthesized using water as a reaction medium, and the effects of AN unit incorporation on the critical gel transition temperature(CGTT) and swelling behaviors of the hydrogels were investigated. The CGTT of the copolymer hydrogel was 30∼32 ℃, decreasing with increasing AN content. Below CGTT, swelling rate and equilibrium swelling ratio of the copolymer hydrogel decreased with increasing AN content. On the other hand, it exhibited faster deswelling and lower equilibrium deswelling ratio with increasing AN content above CGTT.

열 응답성을 갖는 poly(N-isopropylacrylamide)(PNIPAAm) 수화젤의 팽윤 및 수축 특성을 변화시키기 위하여, 물을 용매로 하여 AN 함량이 10 mol% 이내인 P(NIPAAm-co-AN) 공중합체 및 이들의 수화젤을 합성하였고, AN 함량이 공중합체 수화젤의 임계젤전이온도(CGTT) 및 팽윤 거동에 미치는 영향을 분석하였다. 공중합체 수화젤들은 30∼32 ℃에서 CGTT를 나타내었으며, AN 함량이 증가함에 따라 CGTT는 저온 쪽으로 이동하였다. 이들 공중합체 수화젤을 CGTT 이하 온도의 물에서 팽윤시키면 AN 함량이 많아짐에 따라 팽윤속도가 느려지고 평형 팽윤비 값이 작아지지만, CGTT 이상에서 수축시키면 AN 함량이 많은 수화젤이 더 빠르고 더 많이 수축하였다.

Keywords: poly(N-isopropylacrylamide); acrylonitrile; hydrogel; critical gel transition temperature (CGTT); swelling behavior

References
  • 1. Bromberg LV, Ron ES, Adv. Drug Deliv. Rev., 31, 197 (1998)
  •  
  • 2. Heskins M, Guillet JE, J. Macromol. Sci.-Phys., 2, 1441 (1968)
  •  
  • 3. Schild HG, Prog. Polym. Sci, 17, 163 (1992)
  •  
  • 4. Okano T, Bae YH, Kim SW, J. Control. Release, 11, 255 (1990)
  •  
  • 5. Holtz JH, Asher SA, Nature, 389(6653), 829 (1997)
  •  
  • 6. Qiu Y, Park K, Adv. Drug Deliv. Rev., 53, 321 (2001)
  •  
  • 7. Inomata H, Goto S, Otake K, Saito S, Langmuir, 8, 687 (1992)
  •  
  • 8. Kokufuta E, Zhang YQ, Tanaka T, Mamada A, Macromolecules, 26, 1053 (1993)
  •  
  • 9. Kim K, Shin YJ, Polym.(Korea), 18(5), 860 (1994)
  •  
  • 10. Yan Q, Hoffman AS, Polymer, 36(4), 887 (1995)
  •  
  • 11. Zhang XZ, Zhuo RX, Macromol. Chem. Phys., 200, 2602 (1999)
  •  
  • 12. Kaneko Y, Sakai K, Kikuchi A, Yoshida R, Sakurai Y, Okano T, Macromolecules, 28(23), 7717 (1995)
  •  
  • 13. Ebara M, Aoyagi T, Sakai K, Okano T, J. Polym. Sci. A: Polym. Chem., 39(3), 335 (2001)
  •  
  • 14. Matzelle TR, Geuskens G, Kruse N, Macromolecules, 36(8), 2926 (2003)
  •  
  • 15. Diez-Pena E, Quijada-Garrido I, Barrales-Rienda JM, Macromolecules, 36(7), 2475 (2003)
  •  
  • 16. Lee WF, Yeh YC, Eur. Polym. J., 41, 2488 (2005)
  •  
  • 17. Hales M, Barner-Kowollik C, Davis TP, Stenzel MH, Langmuir, 20(25), 10809 (2004)
  •  
  • 18. Topp MDC, Dijkstra PJ, Talsma H, Feijen J, Macromolecules, 30(26), 8518 (1997)
  •  
  • 19. Xu FJ, Kang ET, Neoh KG, Biomaterials, 27, 2787 (2006)
  •  
  • 20. Schilli CM, Zhang MF, Rizzardo E, Thang SH, Chong YK, Edwards K, Karlsson G, Muller AHE, Macromolecules, 37(21), 7861 (2004)
  •  
  • 21. Pyun DK, Lim YH, An JH, Kim D, Lee DS, Polym.(Korea), 20(2), 335 (1996)
  •  
  • 22. Cho HK, Kim BS, Noh ST, Polym.(Korea), 25(2), 186 (2001)
  •  
  • 23. Sahiner N, Eur. Polym. J., 43, 1709 (2007)
  •  
  • 24. Sahiner N, Alb AM, Graves R, Mandal T, McPherson GL, Reed WF, John VT, Polymer, 48(3), 704 (2007)
  •  
  • 25. Mukae K, Sakurai M, Sawamura S, Makino K, Kim SW, Uead I, Shirahama K, J. Phys. Chem., 97, 737 (1993)
  •  
  • 26. O'Neil MJet al. (Ed.), The Merck Index, 13th Ed., Merck & Co., Inc., Whitehouse Station, N. J., p.25 (2001)
  •  
  • 27. Don TM, Chen HR, Carbohyd. Polym., 61, 334 (2005)
  •  
  • 28. Brandrup J, Immergut EHPolymer Handbook, 3rd Ed., Wiley Interscience, N.Y., p.V/57 (1989)
  •  
  • 29. Save NS, Jassal M, Agrawal AK, J. Appl. Polym. Sci., 95(3), 672 (2005)
  •  
  • Polymer(Korea) 폴리머
  • Frequency : Bimonthly(odd)
    ISSN 0379-153X(Print)
    ISSN 2234-8077(Online)
    Abbr. Polym. Korea
  • 2023 Impact Factor : 0.4
  • Indexed in SCIE

This Article

  • 2007; 31(4): 349-355

    Published online Jul 25, 2007

  • Received on May 7, 2007
  • Accepted on Jun 12, 2007