Department of Optometry & Vision Science, College of Bio and Medical Science, Daegu Catholic University, Hayang-Ro 13-13, Gyeongsan, Gyeongbuk 38430, Korea
대구가톨릭대학교 안경광학과
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This study evaluated the characteristics and improved antioxidant duration by manufacturing antioxidant contact lenses using tannic acid, a natural antioxidant, and carrageenan and alginate, which are seaweed polysaccharides. Contact lenses were prepared to contain hydrophilic monomers and tannic acid and were double-networked with alginate and carrageenan. As the tannic acid content increased, the antioxidant activity increased, and the antioxidant duration was increased by the double-network of carrageenan and alginate. As the tannic acid content increased, the water contents, oxygen permeability, and antibacterial effect increased, and protein adsorption decreased. It was confirmed that the physical and chemical properties were improved and the antioxidant duration was extended by double-network of seaweed polysaccharides in contact lenses containing tannic acid.
천연 항산화제인 탄닌산과 해조다당류인 카라기난, 알지네이트를 이용하여 항산화 콘택트렌즈를 제조하여 특성을 평가하고 항산화 지속시간을 개선하고자 한다. 콘택트렌즈는 친수성 단량체들과 탄닌산을 포함하도록 제조하였으며 알지네이트 및 카라기난으로 이중 네트워크화하였다. 탄닌산 함량이 높을수록 항산화성이 증가되었으며, 카라기난과 알지네이트로 이중 네트워크화함으로써 항산화 지속시간이 증가하였다. 탄닌산 함량이 증가할수록 함수율, 산소투과도, 항균효과가 증가하였으며 단백질 흡착이 감소되었다. 탄닌산이 함유된 콘택트렌즈에 해조다당류로 이중 네트워크화함으로써 물리화학적 특성이 개선되고 항산화 지속시간도 연장됨을 확인하였다.
Keywords: contact lens, tannin acid, polysaccharide, alginate, carrageenan, double-network.
2022; 46(6): 775-782
Published online Nov 25, 2022
Department of Optometry & Vision Science, College of Bio and Medical Science, Daegu Catholic University, Hayang-Ro 13-13, Gyeongsan, Gyeongbuk 38430, Korea