Article
  • Synthesis and Biocompatibility of Gelatin-g-Poly(ethyl methacrylate) Copolymer
  • Kim SK, Kim KS, Cheon YC, Moon YU, Kim YJ, Sim SM
  • Gelatin-g-Poly(ethyl methacrylate) 공중합체의 합성과 그의 생체적합성
  • 김상기, 김공수, 전용철, 문용운, 김영준, 심상무
Abstract
the grafting of ethyl methacrylate onto gelatin initiated by potassium persulfate(KPS) redox system was investigated in aqueous solution. The optimum conditions of grafting were observed. and the physical properties and biocompatibility of graft copolymer membrane were examined. The maximum grafting percentage was shown in the reaction condition of 80 min. at 60C. The swelling degree of membrane was decreased. while the tensile strength increased with increase of the grafting percentage. The permeabilities of water vaper and oxygen were determined in the order of 10-9. The biodegradation by bacteria was decreased with increase of the grafting percentage and stopped after 14days.

Gelatin에 potassium persulfate(KPS)를 개시제로 사용하여 수용액중에서 ethyl methacrylate를 그라프트 공중합시켜 그의 최적 중합조건을 찾아냈으며, 인공피부로서의 이용가능성을 검토하기 위해 그라프트 공중합체 막의 물성과 생체적합성을 실험하였다. 그라프트공중합 반응에 있어서 60C에서 80분동안 반응시켰을 때 최대 그라프트율을 나타내었다. 그라프트율이 증가할 수록 막의 팽윤도는 감소하였고, 인장강도는 증가하였다. 수증기 및 산소 투과성은 10-9 범위의 값을 나타내었고 박테리아에 의한 생분해율은 그라프트율이 증가할수록 감소하였으며 약 14일이 지나면 더 이상의 분해가 일어나지 않았다.

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  • Polymer(Korea) 폴리머
  • Frequency : Bimonthly(odd)
    ISSN 0379-153X(Print)
    ISSN 2234-8077(Online)
    Abbr. Polym. Korea
  • 2023 Impact Factor : 0.4
  • Indexed in SCIE

This Article

  • 1990; 14(5): 473-480

    Published online Oct 25, 1990