Article
  • Clay/Acrylamide Hydrogels Having Fucoidan
  • Hwang S, Lee J
  • 푸코이단을 함유한 Clay/아크릴아미드 하이드로젤
  • 황선애, 이종휘
Abstract
Hydrogels have been investigated due to their potential in a myriad of applications. The introduction of functional moiety such as sulfide has expanded their applicability. In this study, an investigation was carried out on the introduction of fucoidan into the hydrogels of clay/acrylamide. In the resulting semi-IPN nanocomposite hydrogels, the linear polysaccharide, fucoidan, has strong ionic interactions with clay. It was also confirmed from simple mixing tests that fucoidan can physically crosslink with clay without chemical crosslinks. In the semi-IPN hydrogels, equilibrium swelling ratio increased with the content of fucoidan. Elastic modulus increased with an initial increase in the content of fucoidan, and decreased with a further increase. The work of fracture results of these hydrogels showed their tough properties. These hydrogels could provide functional properties such as mucoadhesiveness with tunable hydrogel characteristics.

하이드로젤은 다양한 분야에 적용가능한 그 잠재성으로 인해 널리 연구되어 왔다. 특히 설파이드와 같은 기능성기의 도입은 그들의 응용성을 넓혀왔다. 본 연구에서 점토/아크릴아미드 하이드로젤에 푸코이단을 도입하는 연구를 수행하였다. 얻어진 semi-IPN 나노복합 하이드로젤에서 선형사슬형 다당류인 푸코이단은 점토와 강한 이온 상호작용을 가졌다. 단순한 혼합실험에서도 푸코이단은 점토와 화학결합 없이 물리적 가교를 이룰 수 있었다. Semi-IPN 하이드로젤에서 평형팽윤비율은 푸코이단의 함량이 증가함에 따라 증가하였다. 탄성계수는 푸코이단의 함량이 증가함에 따라 초기엔 증가하였고, 더 증가하면 감소하였다. 이러한 하이드로젤의 파괴의 일 값은 강인한 성질을 보여주었다. 본 하이드로젤은 조절 가능한 하이드로젤로서의 성질들과 함께 점막접착성 등의 기능성 특징을 나타낼 수 있다.

Keywords: hydrogel; acrylamide; nanoclay; fucoidan; swelling.

References
  • 1. Pourjavadi A, Mahadvavinia GR, Turk. J. Chem., 30, 595 (2006)
  •  
  • 2. Po R, J. Macromol. Sci. Rev. Macromol. Chem. Phys., 34C, 607 (1994)
  •  
  • 3. Karada˘g E, Saraydin D, Turk. J. Chem., 26, 863 (2002)
  •  
  • 4. Zhao S, Lee MK, Lee JH, J. Macromol. Sci., 47, 580 (2010)
  •  
  • 5. Blanco MD, Garcia O, Olmo R, Teijion JM, Katime I, J. Chromatogr. B., 680, 243 (1996)
  •  
  • 6. Chen J, Park H, Park K, Inc. J. Biomed. Mater. Res., 44, 53 (1999)
  •  
  • 7. Ferreira L, Vidal MM, Gil MH, Chem. Educator., 6, 100 (2001)
  •  
  • 8. Shin BK, Baek EJ, Kim YT, Jeong JW, Nho YC, Lim YM, Park JS, Huh KM, Park JS, Polym.(Korea), 34(5), 459 (2010)
  •  
  • 9. Yuk KY, Kim YT, Im SJ, Garner J, Fu Y, Park K, Park JS, Huh KM, Polym.(Korea), 34(3), 253 (2010)
  •  
  • 10. Muniz EC, Geuskens G, Macromolecules, 34(13), 4480 (2001)
  •  
  • 11. Mishra S, Bajpai R, Katare R, Bajpai AK, Polym. Lett.eXPRESS, 7, 407 (2007)
  •  
  • 12. Okay O, Oppermann W, Macromolecules, 40(9), 3378 (2007)
  •  
  • 13. Haraguchi K, Takehisa T, Fan S, Macromolecules, 35(27), 10162 (2002)
  •  
  • 14. Haraguchi K, Farnworth R, Ohbayashi A, Takehisa T, Macromolecules, 36(15), 5732 (2003)
  •  
  • 15. Haraguchi K, Li HJ, Matsuda K, Takehisa T, Elliott E, Macromolecules, 38(8), 3482 (2005)
  •  
  • 16. Churochkina NA, Starodoubtsev SG, Khokhlov AR, Polymer Gel and Network., 6, 205 (1998)
  •  
  • 17. Liu Y, Zhu MF, Liu XL, Zhang W, Sun B, Chen YM, Adler HJP, Polymer, 47(1), 1 (2006)
  •  
  • 18. Lee WF, Chen YJ, J. Appl. Polym. Sci., 82(10), 2487 (2001)
  •  
  • 19. Zhao S, Lee JH, Macromol. Res., 17(3), 156 (2009)
  •  
  • 20. Lee J, Macosko CW, Urry DW, Macromolecules, 34(17), 5968 (2001)
  •  
  • 21. Cotterell B, Reddel JK, Int. J. Fract., 13, 267 (1997)
  •  
  • 22. Broberg KB, J. Mech. Phys. Solid., 19, 407 (1971)
  •  
  • 23. Kong HJ, Wong E, Mooney DJ, Macromolecules, 36(12), 4582 (2003)
  •  
  • Polymer(Korea) 폴리머
  • Frequency : Bimonthly(odd)
    ISSN 0379-153X(Print)
    ISSN 2234-8077(Online)
    Abbr. Polym. Korea
  • 2022 Impact Factor : 0.4
  • Indexed in SCIE

This Article

  • 2011; 35(4): 332-336

    Published online Jul 25, 2011

  • Received on Jan 28, 2011
  • Accepted on Mar 4, 2011