Article
  • A Study on the Immobilization of Biomolecules on Poly(acrylic acid)-grafted MWCNTs Prepared by Radiation-Induced Graft Polymerization
  • Jung CH, Lee BM, Hwang IT, Choi JH, Nho YC, Hong SK
  • 방사선 그래프트 중합에 의하여 제조된 폴리(아크릴 산)이 그래프트된 탄소나노튜브에 생체분자 고정화에 관한 연구
  • 정찬희, 이병민, 황인태, 최재학, 노영창, 홍성권
Abstract
In this research, biomolecule-immobilized multi-walled carbon nanotubes (MWCNTs) were prepared by using radiation-induced graft polymerization. For the immobilization of biomolecules, the surface of MWNCTs was functionalized by radiation-induced graft polymerization of acrylic acid. Based on the results of TGA and Raman spectroscopy it was found that acrylic acid was effectively graft-polymerized on the MWCNTs. Biomolecules such as DNA and proteins were immobilized onto the resultant poly(acrylic acid)-grafted MWCNTs. The results of the X-ray photoelectron spectroscopy and fluorescence microscopy confirmed that the biomoelcules were successfully immobilized on the poly(acrylic acid)-grafted MWCNTs.

본 연구에서는 방사선에 의한 그래프트 중합을 이용하여 생체분자가 고정화된 다중벽탄소나노튜브 (MWCNT)를 제조하였다. 생체분자의 고정화를 위하여 MWCNT에 아크릴 산을 그래프트 중합하였다. 열중량분석과 라만 분석을 통하여 MWCNT에 폴리(아크릴 산)이 효과적으로 그래프트 중합되었음을 확인하였다. 폴리(아크릴 산)이 그래프트 된 MWCNT에 DNA와 단백질과 같은 생체분자들을 고정화하였다. X-선 광전자 분광법과 형광분석을 통하여 생체분자들이 성공적으로 MWCNT에 도입되었음이 확인되었다.

Keywords: biomolecule; multi-walled carbon nanotube; poly(acrylic acid); radiation-induced graft polymerization

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  • Polymer(Korea) 폴리머
  • Frequency : Bimonthly(odd)
    ISSN 0379-153X(Print)
    ISSN 2234-8077(Online)
    Abbr. Polym. Korea
  • 2023 Impact Factor : 0.4
  • Indexed in SCIE

This Article

  • 2010; 34(2): 150-153

    Published online Mar 25, 2010

  • Received on Nov 12, 2009
  • Accepted on Jan 5, 2010