Article
  • Preparation of Stimuli-Responsive Polymeric Membranes and Their Permeation Characteristics of Drugs : Ⅲ. Functionalization of Polyamide Membranes Prepared by Plasma Polymerization Method and Their Riboflavin and PEG Permeation Characteristics
  • Ihm SY, Lee YM, Kim JH, Kang DM, Cho CS, Sung YK
  • 자극감응성 고분자막의 제조와 약물투과특성 : Ⅲ. 플라즈마중합법에 의한 폴리아미드막의 기능화와 리보플라빈 및 PEG의 투과특성
  • 임성윤, 이영무, 김진홍, 강덕만, 조종수, 성용길
Abstract
Acrylic acid and methacrylic acid were grafted on the surface of commercial polyamide membrane using plasma polymerization method. Graft reaction was confirmed by XPS technique. Graft yield increased with plama treatment time. Permeation of riboflavin and PEG were investigated using graft membranes. Poly(acrylic acid-g-amide)membrane showed a decrease in permeability of solute in pH 4∼5 while poly(methacrylic acid-g-amide) membrane exhibited the decreased permeability in pH 6∼7. Plasma polymerization method was compared with chemical initiation method in terms of solute permeation performances.

폴리아미드 다공성막 표면에 플라즈마를 조사하여 아크릴산과 메타크릴산을 그라프트 중합하고 구조를 XPS로 확인하였다. 플라즈마처리한 시간에 따라 그라프트율이 증가하였으며, 이들 막들을 이용하여 리보플라빈과 PEG의 투과성을 검토하였다. 아크릴산이 중합된 폴리아미드 막은 pH4∼5 범위에서 용질 투과도가 감소하였으며 메타크릴산이 중합된 폴리아미드막은 pH6∼7 위에서 용질투과도의 감소가 일어났다. 화학적개시제를 사용한 경우와 비교 검토하였다.

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  • Polymer(Korea) 폴리머
  • Frequency : Bimonthly(odd)
    ISSN 0379-153X(Print)
    ISSN 2234-8077(Online)
    Abbr. Polym. Korea
  • 2023 Impact Factor : 0.4
  • Indexed in SCIE

This Article

  • 1994; 18(3): 399-405

    Published online May 25, 1994