Article
  • Biodegradation of Atelocollagen in the Articular Cavity
  • Sang Hun Woo , Bo Keun Lee, Hee Sang Roh, Andrew S. Kwak, Jin Hyo Yang, Jun Yeong Park*, and Ji Chul Yoo

  • R&D Division, Cellontech Co., Ltd., Wooyoung Techno Center, 144 Achasan-ro Seongdong-gu, Seoul 04783, Korea
    *Department of Orthopaedic Surgery, Hwaseong Jungang Hospital, 5, Baran-ro, Hyangnam-eup,
    Hwaseong-si, Gyeonggi-do 18592, Korea

  • 아텔로콜라겐의 관절강내 생분해도 확인시험
  • 우상훈 · 이보근 · 노희상 · 앤드류곽 · 양진효 · 박준영* · 유지철

  • 셀론텍㈜ 연구개발본부, *화성중앙병원 정형외과

  • Reproduction, stored in a retrieval system, or transmitted in any form of any part of this publication is permitted only by written permission from the Polymer Society of Korea.

References
  • 1. Heijink, A.; Gomoll, A. H.; Madry, H.; Drobnic, M.; Filardo, G.; Espregueira-Mendes, J.; Dijk, C. N. V. Biomechanical Considerations in the Pathogenesis of Osteoarthritis of the Knee. Knee. Surg. Sprots. Traumatol. Arthrosc. 2012, 20, 423-435.
  •  
  • 2. Maldonado, M.; Nam, J. The Role of Changes in Extracellular Matrix of Cartilage in the Presence of Inflammation on the Pathology of Osteoarthritis. Biomed. Res. Int. 2013, 284873.
  •  
  • 3. Wu, J. P.; Kirk, T. B.; Zheng, M. H. Study of the Collagen Structure in the Superficial Zone and Physiological State of Articular Cartilage using a 3D Confocal Imaging Technique. J. Orthop. Surg. Res. 2008, 3, 29.
  •  
  • 4. Felson, D. T. Osteoarthritis of the Knee. N. Engl. J. Med. 2006, 354, 841-848.
  •  
  • 5. Filardo, G.; Kon, E.; Roffi, A.; Matteo, B. D.; Merli, M. L.; Marcacci, M. Platelet-Rich Plasma: Why Intra-articular? A Systematic Review of Preclinical Studies and Clinical Evidence on PRP for Joint Degeneration. Knee. Surg. Sports. Traumatol. Arthrosc 2015, 23, 2459-2474.
  •  
  • 6. Bhadra, A. K.; Altman, R.; Dasa, V.; Myrick, K.; Rosen, J.; Vad, V.; Vitanzo, P.; Bruno, M.; Kleiner, H.; Just, C. Appropriate use Criteria for Hyaluronic Acid in the Treatment of Knee Osteoarthritis in the United States. Cartilage 2017, 8, 234-254.
  •  
  • 7. Briem, K.; Axe, M. J.; Snyder-Mackler, L. Medial Knee Joint Loading Increases in Those who Respond to Hyaluronan Injection for Medial Knee Osteoarthritis. J. Orthop. Res. 2009, 27, 1420-1425.
  •  
  • 8. Altman, R. D.; Dasa, V.; Takeuchi, J. Review of the Mechanism of Action for Supartz FX in Knee Osteoarthritis. Cartilage 2018, 9, 11-20.
  •  
  • 9. Ozcamdalli, M.; Misir, A.; Kizkapan, T. B.; Uzun, E.; Duygulu, F.; Yazici, C.; Kafadar, I. H. Comparison of Intra-Articular Injection of Hyaluronic Acid and N-Acetyl Cysteine in the Treatment of Knee Osteoarthritis: A Pilot Study. Cartilage 2017, 8, 384-390.
  •  
  • 10. American College of Rheumatology Ad Hoc Committee on Clinical Guidelines. Guidelines for the Management of Rheumatoid Arthritis. Arthritis. Rheum. 1996, 39, 713-722.
  •  
  • 11. Zhang, W.; Nuki, G.; Moskowitz, R. W.; Abramson, S.; Altman, R. D.; Arden, N. K.; Bierma-Zeinstra, S.; Brandt, K. D.; Croft, P.; Doherty, M.; Dougados, M.; Hochberg, M.; Hunter, D. J.; Kwoh, K.; Lohmander, L. S.; Tugwell, P. OARSI Recommendations for the Management of Hip and Knee Osteoarthritis: Part III: Changes in Evidence Following Systematic Cumulative Update of Research Published through January 2009. Osteoarthritis Cartilage 2010, 18, 476-499.
  •  
  • 12. Brown, T. J.; Laurent, U. B.; Fraser, J. R. Turnover of Hyaluronan in Synovial Joints: Elimination of Labelled Hyaluronan from the Knee Joint of The Rabbit. Exp. Physiol. 1991, 76, 125-134.
  •  
  • 13. Levick, J. R. A Method for Estimating Macromolecular Reflection by Human Synovium, using Measurements of Intra-Articular Half-Lives. Ann. Rheum. Dis. 1998, 57, 339-344.
  •  
  • 14. Silver, F. H.; Garg, A. T. Collagen: Characterization, Processing and Medical Applications. Handbook of Biodegradable Polymers;Domb, A. J., Kost, J., Wiseman, D., 1st Eds.; CRC press: Florida, 1998; pp 323-350.
  •  
  • 15. Doppalapudi, S.; Jain, A.; Khan, W.; Domb, A. J. Biodegradable Polymers—an Overview. Polym. Adv. Technol. 2014, 25, 427-435.
  •  
  • 16. Salvatore, L.; Natali, M. L.; Brunetti, C.; Sannino, A.; Gallo, N. An Update on the Clinical Efficacy and Safety of Collagen Injectables for Aesthetic and Regenerative Medicine Applications. Polymers 2023, 15, 1020.
  •  
  • 17. Lee, H. S.; Oh, K. J.; Moon, Y. W.; In, Y.; Lee, H. J.; Kwon, S. Y. Intra-articular Injection of Type I Atelocollagen to Alleviate Knee Pain: A Double-Blind, Randomized Controlled Trial. Cartilage 2021, 13, 1_suppl: 342S-350S.
  •  
  • 18. McPherson, J. M.; Sawamura, S.; Armstrong, R. An Examination of The Biologic Response to Injectable, Glutaraldehyde Cross-Linked Collagen Implants. J. Biomed. Mater. Res. 1986, 20, 93-107.
  •  
  • 19. JoseFonseca, M.; Alsina, M. A.; Reig, F. Coating Liposomes with Collagen (Mr 50000) Increases Uptake into Liver. Biochim. Biophys. Acta. 1996,1279, 259-265.
  •  
  • 20. Maeda, M.; Tani, S.; Sano, A.; Fujioka, K. Microstructure and Release Characteristics of the Minipellet, a Collagen-based Drug Delivery System for Controlled Release of Protein Drugs. J. Control. Release 1999, 62, 313-324.
  •  
  • 21. Puppi, D.; Chiellini, F.; Piras, A. M.; Chiellini, E. Polymeric Materials for Bone and Cartilage Repair. Prog. Polym. Sci. 2010, 35, 403-440.
  •  
  • 22. Suh, D. S.; Yoo, J. C.; Woo, S. H.; Kwak, A. S. Intra-Articular Atelocollagen Injection for The Treatment of Articular Cartilage Defects in Rabbit Model. Tissue. Eng. Regen. Med. 2021, 18, 663-670.
  •  
  • 23. Nakagawa, M.; Tanaka, M.; Miyata, T. Evaluation of Collagen Gel and Hyaluronic Acid as Vitreous Substitutes.Ophthalmic. Res. 1997, 29, 409-420.
  •  
  • 24. Moses, O.; Vitrial, D.; Aboodi, G.; Sculean, A.; Tal, Haim.; Kozlovsky, A.; Artzi, Z.; Weinreb, M.; Nemcovsky, C. E. Biodegradation of Three Different Collagen Membranes in the Rat Calvarium: A Comparative Study. J. Periodontol. 2008, 79, 905-911.
  •  
  • 25. Vallecillo, C.; Toledano-Osorio, Manuel.; Vallecillo-Rivas, M.; Toledano, M.; Osorio, R. In Vitro Biodegradation Pattern of Collagen Matrices for Soft Tissue Augmentation. Polymers 2021, 13, 2633-2650.
  •  
  • 26. Olaechea, A.; Mendoza-Azpur, G.; Valdvia, E.; Rasperini, G.; Biodegradation of Three Different Collagen Mambranes: A Histological Study. J. Osseointeg. 2016, 8, 15-19.
  •  
  • 27. Nguyen, T. T.; Mobashery, S.; Chang, M. Roles of Matrix Metalloproteinases In Cutaneous Wound Healing; Intechopen: London, 2023.
  •  
  • 28. Singh, D.; Rai, V.; Agrawal, D. K. Regulation of Collagen I and Collagen III in Tissue Injury and Regeneration. Cardiology Cardiovascular Medicine 2023, 7, 5-16.
  •  
  • Polymer(Korea) 폴리머
  • Frequency : Bimonthly(odd)
    ISSN 0379-153X(Print)
    ISSN 2234-8077(Online)
    Abbr. Polym. Korea
  • 2023 Impact Factor : 0.4
  • Indexed in SCIE

This Article

  • 2024; 48(4): 413-418

    Published online Jul 25, 2024

  • 10.7317/pk.2024.48.4.413
  • Received on Mar 29, 2024
  • Revised on May 10, 2024
  • Accepted on May 27, 2024

Correspondence to

  • Ji Chul Yoo
  • R&D Division, Cellontech Co., Ltd., Wooyoung Techno Center, 144 Achasan-ro Seongdong-gu, Seoul 04783, Korea

  • E-mail: yjc@cellontech.com