Article
  • Fabrication of Starch-Lauric Acid Nanoparticles for Potential Tumor Therapy

  • Guk-Young Ahn, Inseong Choi, Tae Hoon Yun, and Sung-Wook Choi†

  • Department of Biomedical Chemical Engineering, The Catholic University of Korea, 43 Jibong-ro, Wonmi-gu, Bucheon-si, Gyeonggi-do, Korea

  • 잠재적 종양 치료를 위한 전분-라우르산 나노 입자의 제조

  • 안국영 · 최인성 · 윤태훈 · 최성욱†

  • 가톨릭대학교 바이오메디컬화학공학과

References
  • 1. Hu, C.-M. J.; Aryal, S.; Zhang, L. Nanoparticle-assisted Combination Therapies for Effective Cancer Treatment. Ther. Deliv. 2010, 1, 323-334.
  •  
  • 2. Kim, Y. M.; Lim, S. K.; Yoon, M. S. Paclitaxel-loaded Nanoparticles of Cholanic Acid-Modified Hyaluronan Oligosaccharide for Tumor-site Specific Delivery. Polym. Korea 2015, 39, 967-975.
  •  
  • 3. Bhunia, S. K.; Saha, A.; Maity, A. R.; Ray, S. C.; Jana, N. R. Carbon Nanoparticle-based Fluorescent Bioimaging Probes. Sci. Rep. 2013, 3, 1473.
  •  
  • 4. Singh, R.; Lillard, J. W. Nanoparticle-based Targeted Drug Delivery. Exp. Mol. Pathol. 2009, 86, 215-223.
  •  
  • 5. Park, J. K.; Kim, D. G.; Choi, C.; Jeong, Y. I.; Kim, M. Y.; Jang, M. K.; Nah, J. W. Preparation and Characterization of Lithocholic Acid Conjugated Chitosan Oligosaccharide Nanoparticles for Hydrophobic Anticancer Agent Carriers. Polym. Korea 2008, 32, 263-269.
  •  
  • 6. Cong, D. V.; Trang, N. T. T.; Giang, N. V.; Trung, T. H.; Chinh, N. T.; Huynh, M. D.; Hoang, T.; Park, J.-S. Preparation and Characterization of Nanocomposites Based on Poly(ethylene-co-vinyl acetate), Polylactic Acid, and TiO2 Nanoparticles. Polym. Korea 2016, 40, 355-364.
  •  
  • 7. Kumari, A.; Yadav, S. K.; Yadav, S. C. Biodegradable Polymeric Nanoparticles Based Drug Delivery Systems. Colloid. Surface B 2010, 75, 1-18.
  •  
  • 8. Yan, W.; Huang, L. Recent Advances in Liposome-Based Nanoparticles for Antigen Delivery. Polym. Rev. 2007, 47, 329-344.
  •  
  • 9. Khanal, A.; Inoue, Y.; Yada, M.; Nakashima, K. Synthesis of Silica Hollow Nanoparticles Templated by Polymeric Micelle with Core−Shell−Corona Structure. J. Am. Chem. Soc. 2007, 129, 1534-1535.
  •  
  • 10. Scott, R. W. J.; Wilson, O. M.; Crooks, R. M. Synthesis, Characterization, and Applications of Dendrimer-Encapsulated Nanoparticles. J. Phys. Chem. B 2005, 109, 692-704.
  •  
  • 11. Xu, Z. P.; Zeng, Q. H.; Lu, G. Q.; Yu, A. B. Inorganic Nanoparticles as Carriers for Efficient Cellular Delivery. Chem. Eng. Sci. 2006, 61, 1027-1040.
  •  
  • 12. Torchilin, V. Tumor Delivery of Macromolecular Drugs Based on the EPR Effect. Adv. Drug Deliver. Rev. 2011, 63, 131-135.
  •  
  • 13. Wang, M.; Thanou, M. Targeting Nanoparticles to Cancer. Pharmacol. Res. 2010, 62, 90-99.
  •  
  • 14. Haley, B.; Frenkel, E. Nanoparticles for Drug Delivery in Cancer Treatment. Urol. Oncol.-Semin. O. I. 2008, 26, 57-64.
  •  
  • 15. Dayrit, F. M. The Properties of Lauric Acid and Their Significance in Coconut Oil. J. Am. Oil Chem. Soc. 2015, 92, 1-15.
  •  
  • 16. Odenigbo, U. M.; Otisi, C. A. O. Fatty Acids and Phytochemical Contents of Different Coconut Seed Flesh in Nigeria. Int. J. Plant Physiol. Biochem. 2011, 3, 176-182.
  •  
  • 17. Agoramoorthy, G.; Chandrasekaran, M.; Venkatesalu, V.; Hsu, M. J. Antibacterial and Antifungal Activities of Fatty Acid Methyl Esters of the Blind-your-eye Mangrove from India. Braz. J. Microbiol. 2007, 38, 739-742.
  •  
  • 18. Calder, P. C. Long-chain Fatty Acids and Inflammation. P. Nurt. Soc. 2012, 71, 284-289.
  •  
  • 19. Veeresh Babu, S. V.; Veeresh, B.; Patil, A. A.; Warke, Y. B. Lauric acid and Myristic Acid Prevent Testosterone Induced Prostatic Hyperplasia in Rats. Eur. J. Pharmacol. 2010, 626, 262-265.
  •  
  • 20. Weng, W.-H.; Leung, W.-H.; Pang, Y.-J.; Hsu, H.-H. Lauric Acid Can Improve The Sensitization of Cetuximab in KRAS/BRAF Mutated Colorectal Cancer Cells by Retrievable microRNA-378 Expression. Oncol. Rep. 2016, 35, 107-116.
  •  
  • 21. Lappano, R.; Sebastiani, A.; Cirillo, F.; Rigiracciolo, D. C.; Galli, G. R.; Curcio, R.; Malaguarnera, R.; elfiore, A.; Cappello, A. R.; Maggiolini, M. The Lauric Acid-activated Signaling Prompts Apoptosis in Cancer Cells. Cell Death Discov. 2017, 3, 17063.
  •  
  • 22. Ozben, T. Oxidative Stress and Apoptosis: Impact on Cancer Therapy. J. Pharm. Sci. 2007, 96, 2181-2196.
  •  
  • 23. Matés, J. M.; Segura, J. A.; Alonso, F. J.; Márquez, J. Oxidative Stress in Apoptosis and Cancer: An Update. Arch. Toxicol. 2012, 86, 1649-1665.
  •  
  • 24. Tracey, T. J.; Steyn, F. J.; Wolvetang, E. J.; Ngo, S. T. Neuronal Lipid Metabolism: Multiple Pathways Driving Functional Outcomes in Health and Disease. Front. Mol. Neurosci. 2018, 11, 1-25.
  •  
  • 25. Lu, D. R.; Xiao, C. M.; Xu, S. J. Starch-based Completely Biodegradable Polymer Materials. Express Polym. Lett. 2009, 3, 366–375.
  •  
  • 26. Kunishima, M.; Morita, J.; Kawachi, C.; Iwasaki, F.; Terao, K.; Tani, S. Esterification of Carboxylic Acids with Alcohols by 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methyl-morpholinium Chloride (DMTMM). Synlett. 1999, 8, 1255-1256.
  •  
  • 27. D’Este, M.; Eglin, D.; Alini, M. A Systematic Analysis of DMTMM vs EDC/NHS for Ligation of Amines to Hyaluronan in Water. Carbohydr. Polym. 2014, 108, 239-246.
  •  
  • 28. Lee, J.-H.; Jung, S.-W.; Kim, I.-S.; Jeong, Y.-I.; Kim, Y.-H.; Kim, S.-H. Polymeric Nanoparticle Composed of Fatty Acids and Poly(ethylene glycol) as a Drug Carrier. Int. J. Pharm. 2003, 251, 23-32.
  •  
  • 29. Na, K.; Park, K.-H.; Kim, S. W.; Bae, Y. H. Self-assembled Hydrogel Nanoparticles from Curdlan Derivatives: Characterization, Anti-cancer Drug Release and Interaction with a Hepatoma Cell Line (HepG2). J. Control. Release 2000, 69, 225-236.
  •  
  • 30. Lim, S. A.; Park, H.; Lee, J. M.; Lee, E. S. Chlorin E6-embedded Starch Nanogels for Improved Photodynamic Tumor Ablation. Polym. Adv. Technol. 2018, 29, 2766-2773.
  •  
  • 31. Yang, D.; Pornpattananangkul, D.; Nakatsuji, T.; Chan, M.; Carson, D.; Huang, C.-M.; Zhang, L. The Antimicrobial Activity of Liposomal Lauric Acids Against Propionibacterium Acnes. Biomaterials 2009, 30, 6035-6040.
  •  
  • 32. He, C.; Hu, Y.; Yin, L.; Tang, C.; Yin, C. Effects of Particle Size and Surface Charge on Cellular Uptake and Biodistribution of Polymeric Nanoparticles. Biomaterials 2010, 31, 3657-3666.
  •  
  • 33. Kulkarni, S. A.; Feng, S.-S. Effects of Particle Size and Surface Modification on Cellular Uptake and Biodistribution of Polymeric Nanoparticles for Drug Delivery. Pharm. Res. 2013, 30, 2512-2522.
  •  
  • 34. Win, K. Y.; Feng, S.-S. Effects of Particle Size and Surface Coating on Cellular Uptake of Polymeric Nanoparticles for Oral Delivery of Anticancer Drugs. Biomaterials 2005, 26, 2713-2722.
  •  
  • 35. Zhang, H. Y.; Firempong, C. K.; Wang, Y. W.; Xu, W. Q.; Wang, M. M.; Cao, X.; Zhu, Y.; Tong, S. S.; Yu, J. N.; Xu, X. M. Ergosterol-loaded Poly(lactide-co-glycolide) Nanoparticles with Enhanced In Vitro Antitumor Activity and Oral Bioavailability. Acta Pharmacol. Sin. 2016, 37, 834-844.
  •  
  • 36. Song, S.; Zhang, Y. Carbon Nanotube/reduced Graphene Oxide Hybrid for Simultaneously Enhancing the Thermal Conductivity and Mechanical Properties of Styrene -butadiene Rubber. Carbon 2017, 123, 158-167.
  •  
  • 37. Lehto, V.-P. EGF Receptor: Which Way to Go? FEBS Lett. 2001, 491, 1-3.
  •  
  • 38. Kong, J. Y.; Rabkin, S. W. Lovastatin Does Not Accentuate but is Rather Additive to Palmitate-induced Apoptosis in Cardiomyocytes. Prostag. Leukotr. Ess. 2002, 67, 293-302.
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  • Polymer(Korea) 폴리머
  • Frequency : Bimonthly(odd)
    ISSN 0379-153X(Print)
    ISSN 2234-8077(Online)
    Abbr. Polym. Korea
  • 2023 Impact Factor : 0.4
  • Indexed in SCIE

This Article

  • 2021; 45(1): 62-67

    Published online Jan 25, 2021

  • 10.7317/pk.2021.45.1.62
  • Received on Jul 15, 2020
  • Revised on Aug 26, 2020
  • Accepted on Sep 9, 2020

Correspondence to

  • Sung-Wook Choi

  • Department of Biomedical Chemical Engineering, The Catholic University of Korea, 43 Jibong-ro, Wonmi-gu, Bucheon-si, Gyeonggi-do, Korea

  • E-mail: choisw@catholic.ac.kr